In the early 1990s, most scientists did not think that aging was subject to active regulation by genes. However, exciting results from Dr. Kenyon’s lab showed that a single mutation in the daf-2 gene caused the tiny roundworm C. elegans
Chronological age vs. biological age
Chronological age is the number of years a person has been alive. In contrast, biological age refers to how old a person seems, based on several factors, like how your chromosomes have altered over time. In a study, the researchers
Geroscience the mechanisms of aging and age-related disease
Background: what is Geroscience Geroscience is like a dynamic detective duo! It teams up to solve the mysteries of aging and age-related diseases by exploring their biological roots hand in hand. Their mission? To unlock the secrets of longevity and
Experiments that hint of longer lives
What controls aging? Biochemist Cynthia Kenyon has found a simple genetic mutation that can double the lifespan of a simple worm, C. elegans. The lessons from that discovery and others point to how we might one day significantly extend youthful
Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
Highlights •NMN suppresses age-associated body weight gain and enhances energy metabolism •NMN improves insulin sensitivity, eye function, and other features with no toxicity •NMN prevents age-associated gene expression changes in a tissue-specific manner •NMN is an effective anti-aging intervention that
NAD+ in Aging: The Roles of NR and NMN
Rhonda delves into NAD+: its importance for aging, its decline as we age, and popular NAD+ enhancers like nicotinamide riboside and nicotinamide mononucleotide. NAD+ is vital for survival, with small dietary contributions, but the body mainly recycles it. Everyday life