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Genes can play an essential role in health — a defective gene or genes can make you sick or be fatal. Acknowledging this, scientists have been working for decades on adjusting or replacing faulty genes with healthy ones to treat,
In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock,’ which tracks a person’s biological age. A small clinical study in California has proposed for the first time that it might be possible to reverse the body’s epigenetic
In the early 1990s, most scientists did not think that aging was subject to active regulation by genes. However, exciting results from Dr. Kenyon’s lab showed that a single mutation in the daf-2 gene caused the tiny roundworm C. elegans
Chronological age is the number of years a person has been alive. In contrast, biological age refers to how old a person seems, based on several factors, like how your chromosomes have altered over time. In a study, the researchers
In this episode, Dr. Andrew Huberman is joined by Dr. David Sinclair, a tenured Professor of Genetics at Harvard Medical School and an expert researcher in longevity. Dr. Sinclair is also the author of Lifespan: Why We Age & Why
The way we eat throughout our lives influences the way we age. Science has demonstrated a well-balanced and varied diet full of nutritious foods like fruits and veggies, whole grains, legumes, nuts, and lean proteins; and limited in sugar, salt,
Dr. Felipe Sierra discusses the concept of geroscience, which focuses on the relationship between aging and age-related diseases. He emphasizes the significant increase in human lifespan but also highlights the problem of increased health issues in older individuals. Traditional medicine
Background: what is Geroscience Geroscience is like a dynamic detective duo! It teams up to solve the mysteries of aging and age-related diseases by exploring their biological roots hand in hand. Their mission? To unlock the secrets of longevity and
What controls aging? Biochemist Cynthia Kenyon has found a simple genetic mutation that can double the lifespan of a simple worm, C. elegans. The lessons from that discovery and others point to how we might one day significantly extend youthful
Highlights •NMN suppresses age-associated body weight gain and enhances energy metabolism •NMN improves insulin sensitivity, eye function, and other features with no toxicity •NMN prevents age-associated gene expression changes in a tissue-specific manner •NMN is an effective anti-aging intervention that