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Many individuals hold the mistaken belief that the ability to cure cancer or extend the human lifespan will grant them immortality. Even if we were able to significantly extend human lifespans through advancements in stem cell therapy, gene therapy, or
Telomeres and Telomerase: Unraveling the Mechanisms of Cellular Aging and Prospects for Extending Telomere Length By David Coello, SempreFit, 10/2/2023 Abstract: This scientific research paper delves into the intricate role of telomeres and telomerase in cellular aging processes and explores
Base editing is a complex molecular biology technique that requires specialized knowledge and laboratory equipment. It involves using a modified CRISPR system and a base editor enzyme to change specific DNA base pairs. Here is an overview of the general
“Base editing” and “prime editing” are two advanced genome-editing techniques used in molecular biology and genetic engineering to make precise changes to an organism’s DNA. These techniques offer advantages over traditional methods like CRISPR-Cas9 regarding precision and reducing unintended mutations.
“Some animals exhibit a remarkable lack of aging, prompting the question: can humans achieve the same? The pursuit of immortality hinges on how we define it. It remains a distant fantasy if we envision immortality as an eternal, indestructible existence
DNA methylation and histone acetylation are two epigenetic mechanisms that regulate gene expression. Methylation is adding a methyl group to a cytosine nucleotide in DNA. At the same time, acetylation adds an acetyl group to a lysine residue in a
Abstract Hair graying is a common sign of aging resulting from complex regulation of melanogenesis. Currently, there is no medical treatment available for hair repigmentation. In this article, we review the literature on medication-induced hair repigmentation, discuss the potential mechanisms
In June 2018, the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases and added aging for the first time. The classification of aging as a disease paves the way for new research into novel therapeutics to
Abstract Leigh syndrome is a mitochondrial disease characterized by neurological disorders, metabolic abnormalities, and premature death. There is no cure for Leigh syndrome; therefore, new therapeutic targets are urgently needed. In Ndufs4-KO mice, a mouse model of Leigh syndrome, we