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“Base editing” and “prime editing” are two advanced genome-editing techniques used in molecular biology and genetic engineering to make precise changes to an organism’s DNA. These techniques offer advantages over traditional methods like CRISPR-Cas9 regarding precision and reducing unintended mutations.
“Some animals exhibit a remarkable lack of aging, prompting the question: can humans achieve the same? The pursuit of immortality hinges on how we define it. It remains a distant fantasy if we envision immortality as an eternal, indestructible existence
When tumor suppressor genes mutate, their products no longer inhibit the cell cycle or promote apoptosis (the death of cells occurs as a regular and controlled part of an organism’s growth or development). Therefore, these mutations can be called “loss-of-function,”
Epigenetics has emerged as a promising frontier in the quest to effectively treat various human diseases. It involves modifications to DNA or DNA-associated proteins, like histones, without altering the DNA sequence itself. These modifications play a pivotal role in determining
DNA methylation and histone acetylation are two epigenetic mechanisms that regulate gene expression. Methylation is adding a methyl group to a cytosine nucleotide in DNA. At the same time, acetylation adds an acetyl group to a lysine residue in a
Abstract Background Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function. Objective To prospectively
Abstract Hair graying is a common sign of aging resulting from complex regulation of melanogenesis. Currently, there is no medical treatment available for hair repigmentation. In this article, we review the literature on medication-induced hair repigmentation, discuss the potential mechanisms
Hair color is determined by the amount of a pigment called melanin. An abundance of one type of melanin, called eumelanin, gives people black or brown hair. An abundance of another pigment, called pheomelanin, gives people red hair. Hair color
At least six companies have emerged to help unstick what developers say is a “bottleneck” in advancing complex genetic treatments. Editor’s note: BioPharma Dive, as part of Emerging Biotech Weekly, is taking a closer look at competitive areas of startup activity. We aim
In June 2018, the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases and added aging for the first time. The classification of aging as a disease paves the way for new research into novel therapeutics to